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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WIPF1
All Species:
27.27
Human Site:
S486
Identified Species:
50
UniProt:
O43516
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43516
NP_001070737.1
503
51275
S486
L
A
R
N
E
S
R
S
G
S
N
R
R
E
R
Chimpanzee
Pan troglodytes
XP_001150374
510
51924
S486
L
A
R
N
E
S
R
S
G
S
N
R
R
E
R
Rhesus Macaque
Macaca mulatta
XP_001090880
510
52064
S486
L
A
R
N
E
S
R
S
G
S
N
R
R
E
R
Dog
Lupus familis
XP_545531
517
52682
S500
L
A
R
S
E
T
R
S
G
S
N
R
R
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1I7
493
50062
S476
L
A
R
N
E
S
R
S
G
S
N
R
R
E
R
Rat
Rattus norvegicus
Q6IN36
487
49732
S470
V
A
R
S
E
S
R
S
G
S
N
R
R
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515714
498
50998
S481
L
A
R
S
E
S
R
S
G
S
S
R
R
E
R
Chicken
Gallus gallus
NP_001012935
494
49866
G477
L
A
R
N
E
N
R
G
G
S
A
R
K
E
R
Frog
Xenopus laevis
NP_001079978
426
44520
G417
K
S
I
R
A
T
R
G
V
P
P
L
P
P
I
Zebra Danio
Brachydanio rerio
XP_001919866
485
49016
G471
R
N
E
S
R
G
S
G
K
K
E
R
G
A
P
Tiger Blowfish
Takifugu rubipres
NP_001098701
410
41639
E401
L
S
G
S
G
K
K
E
R
G
A
P
P
P
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195725
392
41038
K382
Q
P
N
R
Q
S
T
K
R
G
Q
P
P
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P37370
817
82575
I508
Q
D
K
Q
E
D
V
I
G
S
S
K
D
D
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.6
85.8
N.A.
88.6
87.4
N.A.
80.9
73.1
40.5
58.6
39.3
N.A.
N.A.
N.A.
35.9
Protein Similarity:
100
98.2
97.6
90.3
N.A.
92
91.6
N.A.
87.2
82.1
50.5
68.1
48.3
N.A.
N.A.
N.A.
42.5
P-Site Identity:
100
100
100
86.6
N.A.
100
86.6
N.A.
86.6
73.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
20
13.3
26.6
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
62
0
0
8
0
0
0
0
0
16
0
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
8
0
70
0
0
8
0
0
8
0
0
62
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
8
8
0
24
70
16
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% I
% Lys:
8
0
8
0
0
8
8
8
8
8
0
8
8
0
0
% K
% Leu:
62
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
39
0
8
0
0
0
0
47
0
0
0
8
% N
% Pro:
0
8
0
0
0
0
0
0
0
8
8
16
24
16
16
% P
% Gln:
16
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
62
16
8
0
70
0
16
0
0
70
54
0
62
% R
% Ser:
0
16
0
39
0
54
8
54
0
70
16
0
0
0
0
% S
% Thr:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _